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Merck
모든 사진(4)

주요 문서

SAB5900201

Sigma-Aldrich

Alpaca Anti-GFP, recombinant single domain Antibody

Recombinant Alpaca(VHH) Nano antibody

동의어(들):

GFP, Green fluorescent protein

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.43

생물학적 소스

alpaca

Quality Level

재조합

expressed in E. coli

결합

unconjugated

항체 형태

affinity purified VHH antibody

클론

GE10, monoclonal

분석

>95% (SDS-PAGE)

양식

lyophilized solid

분자량

13.7 kDa
~15-18 kDa (SDS PAGE under reducing condition)

정제법

immobilized metal affinity chromatography (IMAC)

종 반응성

SARS coronavirus

농도

1 mg/mL

기술

ELISA: 1:2000-1:10000
immunofluorescence: 1:100-1:600
immunoprecipitation (IP): 0.5-4.0 μg
western blot: 1:1000-1:5000

색상

colorless

pH

( in PBS, pH 7.4)

동형

VHH

단백질 ID 수납 번호

UniProt 수납 번호

배송 상태

ambient

저장 온도

2-8°C

타겟 번역 후 변형

unmodified

일반 설명

Green fluorescent protein (GFP) is a protein composed of 238 amino acid residues(26.9kDa) derived from the Jellyfish Aequorea victoria, which emits green light (emission peak at 509nm) when excited by blue light (excitation peak at 395nm). GFP has become an invaluable tool in cell biology research, since its intrinsic fluorescence can be visualized in living cells. EGFP contains the double-amino-acid substitutions Phe-64 to Leu and Ser-65 to Thr (previously published as GFPmut1; PMID: 8707053). In contrast to wtGFP, EGFP has a single, strong, red-shifted excitation peak at 488 nm. Alpaca derived anti-GFP VHH single-domain antibody (molecular weight: 13.7 kDa), expressed in E. coli under conditions free from animal derived components.It has a 6His tag at its C-terminal.
Single-domain antibody (sdAb), also called nano-antibody, is the variable region isolated from the antigen-binding variable domain (VHH) of camelid heavy-chain-only antibody. It lacks light chains and a first constant domain(CH1). This configuration confers a number of unique advantages over conventional monoclonal antibodies. The small size of just 15 kDa (2~4 nm), single-domain antibody is the smallest antigen-binding fragment that can easily penetrate tissues, allowing them to bind epitopes that are inacessible to conventional antibodies. These single-domain antibodies offer superior chemical and thermal stability and increased solubility than conventional antibodies. All our antibodies are tested to ensure the highest level of specificity, sensitivity and reproducibility. Alpaca derived anti-GFP VHH single-domain antibody (molecular weight: 13.7 kDa), expressed in E. coli under conditions free from animal derived components.

특이성

Green fluorescence protein (GFP) and other derivatives of GFP

면역원

Recombinant full length GFP protein

애플리케이션

ELISA, WB, IP, IF

포장

50 µg per vial / 100 µg per vial

물리적 형태

Affinity purified VHH single domain antibody lyophilized from PBS, pH7.4

재구성

Reconstitute the lyophilized antibody with sterile deionized water or with 50% glycerol (ACS grade or better) to a stock solution of 1 mg/mL. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Avoid vigorous shaking or vortexing.

저장 및 안정성

Stable for 1 year at 4°C from date of receipt.

기타 정보

Storage at 4°C; Do not freeze.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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