생물학적 소스
rabbit
Quality Level
material
colorless
클론
4I6K6, monoclonal
양식
liquid
분자량
68 kDa
종 반응성
rat, mouse
농도
3.00 mg/mL
기술
western blot: 1:500 - 1:2000
색상
colorless
동형
IgG
면역원 서열
SPAVQIKIRELYRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSSPVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKN
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... PIAS2(9063)
일반 설명
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2011]
면역원
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PIAS2 (O75928).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
애플리케이션
WB
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
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