SAB5702238

Anti-PD-L1/CD274 Antibody, clone 8F1V6, Rabbit Monoclonal

• 동의어(들): B7-H,B7H1,PDL1,PD-L1,PDCD1L1,PDCD1LG1,CD274
• UNSPSC 코드: 12352203
• NACRES: NA.46

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• material: colorless
• 클론: 8F1V6, monoclonal
• 형태: liquid
• 종 반응성: human
• 농도: 0.65 mg/mL
• 기술: flow cytometry: 1:50 - 1:200
• 색상: colorless
• 동형: IgG
• UniProt 수납 번호: Q9NZQ7
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... PD-L1(29126)

설명

일반 설명

Programmed death-ligand 1 (PD-L1) is a 40kDa type 1 transmembrane protein that suppresses immune system. PD-L1 is expressed in hematopoietic and non-hematopoietic cells including T cells and B cells and various types of tumor cells. PD-L1 binds to its receptor Programmed death 1 (PD1). During infection or inflammation, PD1-PD-L1 interaction is important for preventing autoimmunity. In tumor microenvironments, PD1-PD-L1 interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human cancers. In recent years, PD-L1 has become an important biomarker and immunotherapy target for many types of malignancies.

면역원

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Recombinant protein of human PD-L1/CD274.

애플리케이션

ELISA, WB, FC, Inhibition

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1