SAB5701871

Anti-Phospho-PAK4/PAK5/PAK6-S474/S560/S602 antibody produced in rabbit

• UNSPSC 코드: 12352203
• NACRES: NA.41
• 클론: monoclonal
• application: WB
• 종 반응성: mouse, human
• 기술: western blot: 1:500-1:2000

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 생산 유형: primary antibodies
• 클론: monoclonal
• 양식: liquid
• 종 반응성: mouse, human
• 농도: 1.65 mg/mL
• 기술: western blot: 1:500-1:2000
• UniProt 수납 번호: (O96013(PAK4-Antigen),Q9P286(PAK5),Q9NQU5(PAK6))
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pSer474/pSer560/pSer602)

설명

일반 설명

PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

면역원

A phospho specific peptide corresponding to residues surrounding S474 of human PAK4

물리적 형태

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable