SAB5700581

Anti-Phospho-CSF1R-Y723 antibody produced in rabbit

• 동의어(들): BANDDOS, C-FMS, CD115, CSF-1R, CSF1R, CSFR, FIM2, FMS, HDLS, M-CSF-R
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: 107; 33
• 종 반응성: human
• 농도: 0.76mg/ml
• 기술: western blot: 1:500-1:2000
• UniProt 수납 번호: P07333
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pTyr723)
• 유전자 정보: human ... CSF1R(1436)

설명

일반 설명

The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma.

면역원

A phospho synthetic peptide corresponding to residues surrounding Y723 of human CSF1R.

물리적 형태

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

저장 및 안정성

Store at -20℃. Avoid freeze / thaw cycles.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable