추천 제품
생물학적 소스
rabbit
Quality Level
재조합
expressed in proprietary host
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
SP194, monoclonal
종 반응성
human (tested)
기술
flow cytometry: 1:400
immunoblotting: 1:400
immunohistochemistry: 1:100
동형
IgG
UniProt 수납 번호
배송 상태
wet ice
저장 온도
2-8°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... MAGEA1(4100)
관련 카테고리
일반 설명
Melanoma-associated antigen 1 (MAGE-A1) belongs to the melanoma-associated antigen (MAGE) gene family. It is also termed cancer-testis antigen (CTA) or cancer-germline (CG) gene. The MAGE-A1 gene is mostly expressed in the human germline. It is also expressed in the placenta and various tumor cells. MAGE-A1 gene is located on human chromosome Xq28.
면역원
Synthetic peptide derived from the C-terminus of human MAGE-A1 protein.
생화학적/생리학적 작용
Melanoma-associated antigen 1 (MAGE-A1) stimulates the proliferation and colony formation of melanoma cells. It might modulate the oncogenic C-JUN expression either directly or via the extracellular-signal-regulated kinase (ERK)-mitogen-activated protein kinase (MAPK) signaling pathway. Hence, MAGE-A1 could be a possible therapeutic target for patients with melanoma. It can be a potential marker in the treatment of lung adenocarcinoma (LUAD).
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
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