SAB5500082

Anti-Chromogranin A antibody, Rabbit monoclonal

clone SP12, recombinant, expressed in proprietary host, tissue culture supernatant

• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 재조합: expressed in proprietary host
• 결합: unconjugated
• 항체 형태: tissue culture supernatant
• 항체 생산 유형: primary antibodies
• 클론: SP12, monoclonal
• 종 반응성: human (tested)
• 종 반응성(상동성에 의해 예측): bovine, pig
• 기술: immunohistochemistry: 1:200
• 동형: IgG
• UniProt 수납 번호: P10645
• 배송 상태: wet ice
• 저장 온도: 2-8°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... CHGA(1113)

설명

일반 설명

Chromogranin A (CgA) is a circulating protein liberated by the neuroendocrine system. It is a glycoprotein that is located on human chromosome 14.

Chromogranin A (a protein of 439 amino acid which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, phenochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.

면역원

Recombinant protein encoding human chromogranin A.

생화학적/생리학적 작용

Chromogranin A (CgA) controls vascular physiology and angiogenesis. It modulates the storage and liberation of catecholamine via intracellular (vesiculogenic) and extracellular (catecholamine release–inhibitory) mechanisms. CHGA is essential to generate catecholamine secretory vesicles in chromaffin-lineage PC12 cells and is required to promote a regulated secretion system in nonsecretory cells.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

0.1 ml rabbit monoclonal antibody supplied as tissue culture supernatant in TBS/1% BSA buffer pH 7.5 with less than 0.1% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable