SAB5300151

Monoclonal Anti-AIFM1 antibody produced in mouse

clone 4E7, ascites fluid

• 동의어(들): AIF, AIFM1, COXPD6, MGC111425, PDCD8
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• 결합: unconjugated
• 항체 형태: ascites fluid
• 항체 생산 유형: primary antibodies
• 클론: 4E7, monoclonal
• 분자량: 67 kDa
• 종 반응성: mouse, monkey, human, rat
• 기술: direct ELISA: 1:10,000; flow cytometry: 1:200-1:400; immunohistochemistry: 1:200-1:1,000; indirect immunofluorescence: 1:200-1:1,000; western blot: 1:500-1:2,000
• 동형: IgG2b
• NCBI 수납 번호: NM_001130846
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... AIF(9131)

설명

일반 설명

AIFM1 (apoptosis inducing factor mitochondria associated 1) codes for apoptosis-inducing factor 1(AIF). It is located on human chromosome Xq26.1. AIF is a caspase-independent cell death effector.

면역원

Purified recombinant fragment of human AIF expressed in E.coli.
Mouse monoclonal antibody raised against AIF

생화학적/생리학적 작용

AIFM1 (apoptosis inducing factor mitochondria associated 1) possesses redox activity, which helps in oxidative phosphorylation. In the mitochondria, AIFM1 helps in assembling or maintaining the mitochondrial respiratory complexes I and III. It plays a vital role in apoptosis. This gene is associated with COXPD6 (combined oxidative phosphorylation deficiency, encephalomyopathy, Cowchock syndrome and X-linked deafness with neuropathy.

물리적 형태

Ascitic fluid containing 0.03% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable