SAB5200074
Monoclonal Anti-SCN2A1 antibody produced in mouse
clone S69-3, 1 mg/mL, purified immunoglobulin
동의어(들):
Anti-NachII, Anti-Nav1.2, Anti-Nav1.2, S69-3, Anti-SCN, Anti-SCN2A, Anti-Scpll
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모든 사진(2)
About This Item
UNSPSC 코드:
12352203
NACRES:
NA.41
결합:
unconjugated
application:
IHC
IP
WB
IP
WB
클론:
S69-3, monoclonal
종 반응성:
human, rat, mouse
citations:
3
기술:
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
immunoprecipitation (IP): suitable
western blot: suitable
추천 제품
생물학적 소스
mouse
Quality Level
결합
unconjugated
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
S69-3, monoclonal
양식
buffered aqueous glycerol solution
분자량
antigen predicted mol wt 250 kDa
종 반응성
human, rat, mouse
농도
1 mg/mL
기술
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
동형
IgG2a
NCBI 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
rat ... Scn2a1(24766)
관련 카테고리
일반 설명
Sodium voltage-gated channel α subunit 2 (SCN2A1) is expressed in the axons and nerve terminals of the rat brain. The gene ID for the protein is 24766.
특이성
Detects ~250 kDa.
면역원
Fusion protein amino acids 1882-2005 (cytoplasmic C-terminus) of rat Nav1.2
애플리케이션
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Western Blotting (1 paper)
Immunofluorescence (1 paper)
Western Blotting (1 paper)
Monoclonal anti-SCN2A1 antibody produced in mouse has been used for immunofluorescence and Western blotting.
생화학적/생리학적 작용
Sodium voltage-gated channel α subunit 2 (SCN2A1) may associate with a number of other proteins in the rat brain. It regulates the conductance of action potentials and also controls the release of neurotransmitters.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Norelle C Wildburger et al.
Molecular & cellular proteomics : MCP, 14(5), 1288-1300 (2015-03-01)
Voltage-gated sodium channels (Nav1.1-Nav1.9) are responsible for the initiation and propagation of action potentials in neurons, controlling firing patterns, synaptic transmission and plasticity of the brain circuit. Yet, it is the protein-protein interactions of the macromolecular complex that exert diverse
Je-Hyun Baek et al.
The Journal of biological chemistry, 289(22), 15363-15373 (2014-04-17)
Voltage-gated sodium (Nav) channels initiate action potentials in brain neurons and are primary therapeutic targets for anti-epileptic drugs controlling neuronal hyperexcitability in epilepsy. The molecular mechanisms underlying abnormal Nav channel expression, localization, and function during development of epilepsy are poorly
Jun Xiang et al.
Molecular medicine reports, 9(1), 16-22 (2013-11-14)
In order to evaluate SCN2A as a candidate gene for epileptic susceptibility and the use of a Cu-Zn superoxide dismutase (SOD) supplement as a potential therapy for epilepsy, SCN2A expression in the cortex and the correlation between SCN2A and Cu-Zn
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