SAB4702140

Monoclonal Anti-CD1a, purified produced in mouse

• 동의어(들): FCB6, HTA1, Leu-6, T6
• UNSPSC 코드: 12352203

속성

• 결합: unconjugated
• Quality Level: 100
• 항체 생산 유형: primary antibodies
• 클론: SK9, monoclonal
• 형태: buffered aqueous solution
• 종 반응성: human
• 농도: 1 mg/ml
• 기술: flow cytometry: suitable; immunoprecipitation (IP): suitable
• 동형: IgG2bκ
• UniProt 수납 번호: P06126
• 저장 온도: 2-8°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... CD1A(909)

설명

일반 설명

CD1a, together with CD1b and c, belongs to group 1 of CD1 glycoproteins. These proteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity. Unlike CD1b, CD1a is excluded from late endosomal compartments and instead traffics independently in the recycling pathway of the early endocytic system, and CD1a antigen presentation is independent upon vesicular acidification.

특이성

The mouse monoclonal antibody SK9 recognizes an extracellular epitope of CD1a (T6), a 49 kDa polypeptide associated with beta2-microglobulin expressed on cortical thymocytes (strongly), Langerhans cells, dendritic cells and some T cell leukemias and lymphomas.

면역원

Human thymocytes

물리적 형태

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

제조 메모

Purified by protein-A affinity chromatography.

저장 및 안정성

Store at 2-8°C. Do not freeze.

기타 정보

The antibody solution should be gently mixed before use.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable