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Merck
모든 사진(1)

주요 문서

SAB4700320

Sigma-Aldrich

Monoclonal Anti-HLA-G antibody produced in mouse

clone MEM-G/11, purified immunoglobulin, buffered aqueous solution

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

결합

unconjugated

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

MEM-G/11, monoclonal

양식

buffered aqueous solution

종 반응성

human

농도

1 mg/mL

기술

flow cytometry: suitable

동형

IgG1

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

2-8°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... HLA-G(3135)

일반 설명

The antibody MEM-G/11 recognizes HLA-G1 antigen. HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells.

면역원

Recombinant human HLA-G refolded with beta2-microglobulin and peptide

애플리케이션

The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 2 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

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Storage Class Code

10 - Combustible liquids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Jonathan E Boyson et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(25), 16180-16185 (2002-11-28)
HLA-G is a nonclassical class I MHC molecule with an unknown function and with unusual characteristics that distinguish it from other class I MHC molecules. Here, we demonstrate that HLA-G forms disulfide-linked dimers that are present on the cell surface.
Jay M Bolnick et al.
Fertility and sterility, 102(1), 135-142 (2014-05-16)
To use trophoblast cells accumulating in the endocervical canal at the beginning of pregnancy for noninvasive prenatal testing. Prospective, double-blinded test for fetal gender. Academic medical center. Fifty-six women with singleton pregnancies at gestational age 5-20 weeks. Isolation of fetal
Nele Gao et al.
Arthritis & rheumatology (Hoboken, N.J.), 66(10), 2849-2861 (2014-06-20)
B cells with immunoregulatory properties (Breg cells) have been described in mice, but their role in the control of human immune responses is not well defined. We recently identified a human population of activated FSC(high) B cells that exhibited regulatory
Natasja Nielsen et al.
Immunology, 142(4), 581-593 (2014-03-29)
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and synovial hyperplasia leading to progressive joint destruction. Fibroblast-like synoviocytes (FLS) are central components of the aggressive, tumour-like synovial structure termed pannus, which invades the joint space and cartilage.

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