SAB4600050
Monoclonal Anti-Fluorescein (FITC) IgG, CF™ 488A antibody produced in mouse
~2 mg/mL, clone 1F8.-1E4, purified immunoglobulin
동의어(들):
Anti Fluorescein Antibody, Anti Fluorescein Antibody - Monoclonal Anti-Fluorescein (FITC) IgG, CF™488A antibody produced in mouse
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모든 사진(1)
About This Item
추천 제품
생물학적 소스
mouse
Quality Level
결합
CF™ 488A conjugate
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
1F8.-1E4, monoclonal
형태
buffered aqueous solution
농도
~2 mg/mL
기술
indirect immunofluorescence: 1-10 μg/mL
동형
IgG1κ
형광
λex 490 nm; λem 515 nm
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
일반 설명
Immunoglobulin G (IgG) belongs to the immunoglobulin family and consists of a gamma (g) heavy chain in the constant (C) region. IgG is a widely expressed serum antibody. The monomeric structure of IgG constitutes two identical heavy chains and two identical light chains with a molecular weight of 50kDa and 25kDa respectively, the primary structure of this antibody also contains disulfide bonds involved in linking the two heavy chains, linking the heavy and light chains and resides inside the chains. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4 with different heavy chains, named g1,g2, g3, and g4, respectively. IgG is produced and released from CD5+B cells, the predominant lymphocytes in the neonatal cell repertoire.
특이성
Binds fluorescein
면역원
fluorescein
애플리케이션
Monoclonal Anti-Fluorescein (FITC) IgG, CF™ 488A antibody produced in mouse has been used in Off-chip miRNA targeting and On-chip miRNA cleavage.
생화학적/생리학적 작용
Maternal IgG is the only antibody transported across the placenta to the fetus. Maternal IgG passively immunizes the infants.
CF™ dyes are a series of highly water-soluble fluorescent dyes, with wavelength extended over the visible and near-infrared (IR) spectrum for labeling biomolecules, mainly proteins and nucleic acids. The primary structure of the CF™ dyes is either cyanine dyes or rhodamine dyes. CF™ 633 produces the brightest antibody conjugates among spectrally similar dyes when excited by the 633nm He-Ne laser or the 635nm red diode laser. The most important advantage of CF™ 633 is its excellent photostability. The molecular weight of CF™ 633 is ~820 and its absorption/emission maxima are at 630/650nm.
CF™ dyes are a series of highly water-soluble fluorescent dyes, with wavelength extended over the visible and near-infrared (IR) spectrum for labeling biomolecules, mainly proteins and nucleic acids. The primary structure of the CF™ dyes is either cyanine dyes or rhodamine dyes. CF™ 633 produces the brightest antibody conjugates among spectrally similar dyes when excited by the 633nm He-Ne laser or the 635nm red diode laser. The most important advantage of CF™ 633 is its excellent photostability. The molecular weight of CF™ 633 is ~820 and its absorption/emission maxima are at 630/650nm.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Supplied in phosphate buffered saline with 0.05% sodium azide, 50% glycerol and 2 mg/mL bovine serum albumin.
제조 메모
Protect from light.
법적 정보
This product is distributed by Sigma-Aldrich Co. under the authorization of Biotium, Inc. This product is covered by one or more US patents and corresponding patent claims outside the US patents or pending applications owned or licensed by Biotium, Inc. including without limitation: 12/334,387; 12/607,915; 12/699,778; 12/850,578; 61/454,484. In consideration of the purchase price paid by the buyer, the buyer is hereby granted a limited, non-exclusive, non-transferable license to use only the purchased amount of the product solely for the buyer′s own internal research in a manner consistent with the accompanying product literature. Except as expressly granted herein, the sale of this product does not grant to or convey upon the buyer any license, expressly, by implication or estoppel, under any patent right or other intellectual property right of Biotium, Inc. Buyer shall not resell or transfer this product to any third party, or use the product for any commercial purposes, including without limitation, any diagnostic, therapeutic or prophylactic uses. This product is for research use only. Any other uses, including diagnostic uses, require a separate license from Biotium, Inc. For information on purchasing a license to use this product for purposes other than research, contact Biotium, Inc., 3159 Corporate Place, Hayward, CA 94545, Tel: (510) 265-1027. Fax: (510) 265-1352. Email: btinfo@biotium.com.
CF is a trademark of Biotium, Inc.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
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Natural antibodies arise independently of known antigenic stimulation, are mostly IGM, polyreactive, and are generally encoded by V genes in germline configuration. Polyreactive IgM natural antibodies are produced by mainly B-1 cells which account for most of the B cell
Human placental Fc receptors and the transmission of antibodies from mother to fetus.
Journal of Reproductive Immunology, 37(1), 1-23 (1997)
Antibody structure, instability, and formulation.
Journal of Pharmaceutical Sciences, 96(1), 1-26 (2007)
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