SAB4504536

Anti-phospho-Src (pTyr⁴¹⁸) antibody produced in rabbit

affinity isolated antibody

• 동의어(들): Anti-ASV, Anti-SRC1, Anti-THC6, Anti-c-SRC, Anti-p60-Src
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: antigen 59 kDa
• 종 반응성: human, mouse, rat
• 농도: ~1 mg/mL
• 기술: ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI 수납 번호: P12931
• UniProt 수납 번호: P12931
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pTyr418)
• 유전자 정보: human ... SRC(6714)

설명

일반 설명

SRC (proto-oncogene, non-receptor tyrosine kinase) belongs to the Src family kinases (SFKs). It contains an amino-terminal domain, conserved Src-homology domains (SH2 and SH3), a tyrosine kinase domain and the carboxyl-terminus. This gene is located on human chromosome 20q11.

면역원

The antiserum was produced against synthesized peptide derived from human Src around the phosphorylation site of Tyr418.

Immunogen Range: 386-435

애플리케이션

Anti-phospho-Src (pTyr418) antibody has been used in immunofluorescence.

생화학적/생리학적 작용

SRC (proto-oncogene, non-receptor tyrosine kinase) controls early HIV-1 (human immunodeficiency virus 1) infection post-entry. This gene participates in fundamental physiological and pathological processes like carcinogenesis and tumor progression. Src kinase activity helps in the migration of endothelial cells.

특징 및 장점

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물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable