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Merck
모든 사진(2)

주요 문서

SAB4504126

Sigma-Aldrich

Anti-phospho-Caspase 3 (pSer150) antibody produced in rabbit

affinity isolated antibody

동의어(들):

Anti-CASP-3, Anti-Caspase-3

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

분자량

antigen 31 kDa

종 반응성

mouse, rat, human

농도

~1 mg/mL

기술

ELISA: 1:40000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

phosphorylation (pSer150)

유전자 정보

human ... CASP3(836)

관련 카테고리

일반 설명

Caspase-3 (CASP3) belongs to the class of cysteine proteases. CASP3 is an executioner caspase, which is cleaved and activated with the help of caspase-8 and caspase-9 initiator caspases. CASP3 is mapped to human chromosome 4q35.1.

면역원

The antiserum was produced against synthesized peptide derived from human Caspase 3 around the phosphorylation site of Ser150.

Immunogen Range: 116-165

생화학적/생리학적 작용

Caspase-3 (CASP3) can degenerate multiple cellular proteins and results in morphological changes and DNA fragmentation in cells at the time of apoptosis. It participates in the growth stimulation. CASP3 plays a major role in the execution phase of apoptosis.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Expression levels of cleaved caspase-3 and caspase-3 in tumorigenesis and prognosis of oral tongue squamous cell carcinoma.
Liu PF, et al.
PLoS ONE, 12(7), e0180620-e0180620 (2017)
Caspase 3?mediated stimulation of tumor cell repopulation during cancer radiotherapy.
Huang Q, et al.
Nature Medicine, 17(7), 860?866-860?866 (2011)
CASP3 gene single-nucleotide polymorphism (rs72689236) and Kawasaki disease in Taiwanese children.
Kuo HC, et al.
Journal of Human Genetics, 56(2), 161?165-161?165 (2011)
Identification of SMURF1 as a possible target for 7q21. 3?22.1 amplification detected in a pancreatic cancer cell line by in?house array?based comparative genomic hybridization.
Suzuki A, et al.
Cancer Science, 99(5), 986-994 (2008)

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