SAB4503836

Anti-phospho-STAT2 (pTyr⁶⁹⁰) antibody produced in rabbit

affinity isolated antibody

• 동의어(들): Anti-IMD44, Anti-ISGF-3, Anti-P113, Anti-PTORCH3, Anti-STAT113
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: antigen 97 kDa
• 종 반응성: human, mouse, rat
• 농도: ~1 mg/mL
• 기술: ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI 수납 번호: P52630
• UniProt 수납 번호: P52630
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pTyr690)
• 유전자 정보: human ... STAT2(6773)

설명

일반 설명

STAT2 (signal transducer and activator of transcription 2) is mapped to human chromosome 12.

Signal transducer and activator of transcription 2 (STAT2) belongs to the STAT family. The gene is located on human chromosome 12q13.3. STAT2 consists of 24 exons and has a molecular weight of 113 kDa. It consists of N-terminal domain (N), coiled-coil domain (CC), DNA-binding domain (DBD), linker domain (L), Src homology 2 domain (SH2), tyrosine phosphorylation site (Y) and transcriptional activation domain (TAD).

면역원

The antiserum was produced against synthesized peptide derived from human STAT2 around the phosphorylation site of Tyr690.

Immunogen Range: 656-705

애플리케이션

Anti-phospho-STAT2 (pTyr690) antibody produced in rabbit has been used in western blotting, immunofluorescence staining and flow cytometric staining.

Anti-phospho-STAT2 (pTyr⁶⁹⁰) antibody produced in rabbit has been used:

• for western blotting
• for immunofluorescence staining
• for flow cytometric staining

생화학적/생리학적 작용

STAT2 (signal transducer and activator of transcription 2) participates in immunity. It plays a major role in interferon signaling pathways.

Signal transducer and activator of transcription 2 (STAT2) is activated by interferon-1 (IFN-I) and IFN-III. It aids protein-protein interactions and is essential for binding IRF9. STAT2 is required for the nuclear export of STAT2-IFN regulatory factor 9 (IRF9) and IFN-stimulated gene factor 3 (ISGF3). It plays a vital role in interactions with STAT1.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable