SAB4503615

Anti-EDG5 antibody produced in rabbit

affinity isolated antibody

• 동의어(들): Endothelial differentiation G-protein coupled receptor 5, S1P receptor Edg-5, S1P2, Sphingosine 1-phosphate receptor 2, Sphingosine 1-phosphate receptor Edg-5
• MDL number: MFCD02686109
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: antigen 38 kDa
• 종 반응성: rat, human, mouse
• 농도: ~1 mg/mL
• 기술: ELISA: 1:40000; western blot: 1:500-1:1000
• NCBI 수납 번호: O95136
• UniProt 수납 번호: O95136
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... S1PR2(9294)

설명

일반 설명

Anti-EDG5 Antibody detects endogenous levels of total EDG5 protein.
EDG5/ S1PR2 (sphingosine-1-phosphate receptor 2), a pleiotropic lipid mediator is abundantly expressed in most of the tissues. S1PR2 codes for a 353 amino acid sphingosine-1-phosphate receptor 2 and is located on human chromosome 19p13.2.

면역원

The antiserum was produced against synthesized peptide derived from human EDG5.

Immunogen Range: 261-310

생화학적/생리학적 작용

In NB (neuroblastoma), EDG5/ S1PR2 (sphingosine-1-phosphate receptor 2) helps in the expression of S1P-induced vascular endothelial growth factor. It promotes the Rho/Rho-kinase pathway. S1PR2 participates in S1P-induced platelet aggregation. S1PR2 is essential for normal auditory function as it is a part of the sphingosine-1-phosphate signaling (S1P) pathway.

특징 및 장점

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물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable