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Merck
모든 사진(2)

주요 문서

SAB4503227

Sigma-Aldrich

Anti-OR51E2 antibody produced in rabbit

affinity isolated antibody

동의어(들):

HPRAJ, OR51E2, Olfactory receptor 51E2, Olfactory receptor OR11-16, Prostate-specific G-protein coupled receptor

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

분자량

antigen 35 kDa

종 반응성

rat, human

농도

~1 mg/mL

기술

ELISA: 1:10000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000

NCBI 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... O51E2(81285)

관련 카테고리

일반 설명

Anti-OR51E2 Antibody detects endogenous levels of total OR51E2 protein.

OR51E2 (olfactory receptor family 51 subfamily E member 2),also known as PSGR, codes for a G-protein–coupled receptor. It is a member of the odorant receptors family. OR51E2 is present in early endosomes. It is mapped to human chromosome 11p15.

면역원

The antiserum was produced against synthesized peptide derived from human OR51E2.

Immunogen Range: 221-270

생화학적/생리학적 작용

OR51E2 (olfactory receptor family 51 subfamily E member 2) helps to mediate rapid, non-genomic, steroidal signaling in prostate cancer cells. It also promotes the growth of early prostate cancer.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Functional Characterization of the Odorant Receptor 51E2 in Human Melanocytes
Gelis L, et al.
The Journal of Biological Chemistry, 291(34), 17772-17786 (2016)
Lian Gelis et al.
Experimental dermatology, 26(7), 569-576 (2017-02-14)
We identified the olfactory receptor 51E2 in human melanoma and have measured both OR51E2 mRNA and protein expression in melanoma tissue sections. qPCR analysis revealed that the receptor is upregulated in melanoma cells compared to normal melanocytes, indicating that OR51E2
The Cancer Genome Atlas Clinical Explorer: a web and mobile interface for identifying clinical-genomic driver associations
Lee H, et al.
Genome Medicine, 7(1), 112-112 (2015)
Nikolina Jovancevic et al.
Frontiers in physiology, 8, 888-888 (2017-12-19)
The odorant receptor 51E2 (OR51E2), which is well-characterized in prostate cancer cells and epidermal pigment cells, was identified for the first time as the most highly expressed OR in human fetal and adult retinal pigment epithelial (RPE) cells. Immunofluorescence staining
Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers
Weng J, et al.
International Journal of Cancer. Journal International Du Cancer, 113(5), 811-818 (2005)

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