추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
분자량
antigen 31 kDa
종 반응성
human, mouse
농도
~1 mg/mL
기술
ELISA: 1:1000
western blot: 1:500-1:1000
NCBI 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... TSG6(7130)
일반 설명
Anti-TSG6 Antibody detects endogenous levels of total TSG6 protein.
Tumor necrosis factor (TNF)-α–stimulated gene 6 protein (TSG-6) is an inflammation-associated secreted protein. It has a molecular weight of about 35 kDa. TSG-6 possesses Link and CUB_C domains, along with a with a short amino-terminal sequence. The gene encoding this protein is localized on human chromosome 2q23.3.
면역원
The antiserum was produced against synthesized peptide derived from human TSG6.
Immunogen Range: 21-70
Immunogen Range: 21-70
생화학적/생리학적 작용
Tumor necrosis factor (TNF)-α–stimulated gene 6 protein (TSG-6) has been implicated in regulation of cell-cell and cell-matrix interactions during inflammation and tumorigenesis. TSG-6 possesses anti-inflammatory properties. It is also known to reduce inflammatory reactions triggered by ischemia in the heart. Thus, it might have a potential role in treating heart disease with other cells such as skeletal myoblasts, fetal myoblasts and embryonic stem cells.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
The anti-inflammatory protein TSG-6 regulates chemokine function by inhibiting chemokine/glycosaminoglycan interactions.
The Journal of Biological Chemistry (2016)
A Novel Allelic Variant of the Human TSG-6 Gene Encoding an Amino Acid Difference in the CUB Module CHROMOSOMAL LOCALIZATION, FREQUENCY ANALYSIS, MODELING, AND EXPRESSION.
The Journal of Biological Chemistry, 277(18), 15354-15362 (2002)
A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44.
The Journal of Cell Biology, 116(2), 545-557 (1992)
Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6.
Cell Stem Cell, 5(1), 54-63 (2009)
Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-κB signaling in resident macrophages
Blood (2011)
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