추천 제품
생물학적 소스
rabbit
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
분자량
antigen 125 kDa
종 반응성
mouse, human
농도
~1 mg/mL
기술
ELISA: 1:5000
immunohistochemistry: 1:50-1:100
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... TEK(7010)
일반 설명
Anti-TIE2 Antibody detects endogenous levels of total TIE2 protein.
The TIE2 (TEK receptor tyrosine kinase) gene is mapped to human chromosome 9p21.2. It is predominantly expressed in the Schlemm′s canal endothelial of the eye.
면역원
The antiserum was produced against synthesized peptide derived from human TIE2.
Immunogen Range: 1068-1117
Immunogen Range: 1068-1117
생화학적/생리학적 작용
Tie-2 (TEK receptor tyrosine kinase) protein induces angiogenesis (both developmental and tumor) and supports endothelial cell survival, upon binding of angiopoietin-1 (an endothelial growth factor) to the receptor. Tie-2 is necessary for Schlemm′s canal formation. The gene regulates vascular homeostasis by involving in auto or transphosphorylation.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
적합한 제품을 찾을 수 없으신가요?
당사의 제품 선택기 도구.을(를) 시도해 보세요.
Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Impaired angiopoietin/Tie2 signaling compromises Schlemm's canal integrity and induces glaucoma.
Kim J
The Journal of Clinical Investigation, 127(10), 3877-3896 (2017)
Angiopoietin-2 and soluble Tie-2 receptor plasma levels in children with obstructive sleep apnea and obesity.
Gozal D
Obesity (Silver Spring, Md.), 25(6), 1083-1090 (2017)
Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity.
Souma T
The Journal of Clinical Investigation, 126(7), 2575-2587 (2016)
Hisashi Takada et al.
Cancer science, 96(2), 100-110 (2005-02-23)
We performed genome-wide screening for deoxyribonucleic acid copy-number aberrations in 31 gastric cancer (GC) cell lines by using custom-made comparative genomic hybridization (CGH)-array. Copy-number gains were frequently detected at 1q, 3q, 5p, 7p, 7q, 8q, 11q, 17q, 20p, 20q, Xp
Jaeryung Kim et al.
Science advances, 5(2), eaau6732-eaau6732 (2019-02-23)
Choriocapillary loss is a major cause of neovascular age-related macular degeneration (NV-AMD). Although vascular endothelial growth factor (VEGF) blockade for NV-AMD has shown beneficial outcomes, unmet medical needs for patients refractory or tachyphylactic to anti-VEGF therapy exist. In addition, the
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.