SAB4502803

Anti-GLUT1 antibody produced in rabbit

affinity isolated antibody

• 동의어(들): GLUT-1, Glucose transporter type 1 erythrocyte/brain, HepG2 glucose transporter, SLC2A1, Solute carrier family 2 facilitated glucose transporter member 1
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: antigen 54 kDa
• 종 반응성: mouse, human, rat
• 농도: ~1 mg/mL
• 기술: ELISA: 1:40000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI 수납 번호: P11166
• UniProt 수납 번호: P11166
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... SLC2A1(6513)

설명

일반 설명

Anti-GLUT1 Antibody detects endogenous levels of total GLUT1 protein.

GLUT1 (Glucose transporter type 1) gene is located on human chromosome 1p34.2. It is expressed in cerebral endothelial cells.

면역원

The antiserum was produced against synthesized peptide derived from human GLUT1.

Immunogen Range: 441-490

애플리케이션

Anti-GLUT1 antibody produced in rabbit has been used

• for protein extraction
• in western blotting
• for immunohistochemistry

Anti-GLUT1, C-Terminal antibody is suitable for use in western blot and immunohistochemistry.

생화학적/생리학적 작용

GLUT1 (Glucose transporter type 1) functions as a receptor for human T-cell leukemia virus (HTLV) I and II. It plays a key role in HTLV-envelope mediated infection. GLUT1 is associated with paroxysmal exertion-induced dyskinesia. Glut1 may regulate cerebral microvasculature, proliferation of endothelial cells and the development of junctional complexes of the BBB (blood-brain barrier). It transports glucose across the BBB.

GLUT1 is a membrane protein that regulates the facilitative transport of glucose across the cells. Mutations in the gene encoding GLUT1 have been linked to epilepsy and diabetic nephropathy . Increased expression of GLUT1 has been associated with tumor differentiation in breast and endometrial cancers, whereas decreased GLUT1 function causes GLUT1 deficiency syndrome . Anti-GLUT1, C-Terminal antibody can be used to detect endogenous levels of total GLUT1 protein. The antibody specifically reacts with GLUT1 in mice, rats and humans.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable