추천 제품
생물학적 소스
rabbit
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
분자량
antigen 44 kDa
종 반응성
mouse, human, rat
농도
~1 mg/mL
기술
ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... KRT19(3880)
관련 카테고리
일반 설명
Anti-Keratin 19 Antibody detects endogenous levels of total Keratin 19 protein.
Cytokeratin 19 (KRT19) is a cytoplasmic intermediate filament protein with a α-helical central domain. It belongs to the acidic type I cytokeratin family of proteins (KRTs). This gene is mapped to human chromosome 17q21.
면역원
The antiserum was produced against synthesized peptide derived from human Keratin 19.
Immunogen Range: 231-280
Immunogen Range: 231-280
생화학적/생리학적 작용
Cytokeratin 19 (KRT19) plays a major role in structural rigidity and multipurpose scaffolds. Overexpression of this gene in various cancers may participate in tumorigenic transformation. It may modulate signaling pathways and mediate cell apoptosis, cell cycle arrest, invasion and metastasis. KRT19 plays a vital role in the cancer stemness of hepatocellular carcinoma (HCC).
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
The tissue-dependent keratin 19 gene transcription is regulated by GKLF/KLF4 and Sp1
Brembeck FH and Rustgi AK
Test, 275(36), 28230-28239 (2000)
Cytokeratin 19 (KRT19) has a role in the reprogramming of cancer stem cell-like cells to less aggressive and more drug-sensitive cells
Saha S, et al.
International Journal of Molecular Sciences, 19(5), 1423-1423 (2018)
Cansu Tekin et al.
Molecular oncology, 15(11), 3091-3108 (2021-05-02)
Pancreatic acinar cells have high plasticity and can transdifferentiate into ductal-like cells. This acinar-to-ductal metaplasia (ADM) contributes to tissue maintenance but may also contribute to the premalignant transformation that can eventually progress to pancreatic ductal adenocarcinoma (PDAC). Macrophages are key
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