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Merck
모든 사진(3)

Key Documents

SAB4501662

Sigma-Aldrich

Anti-Keratin 17 antibody produced in rabbit

affinity isolated antibody

동의어(들):

CK-17, Cytokeratin-17, K17, Keratin type I cytoskeletal 17

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

분자량

antigen 48 kDa

종 반응성

mouse, rat, human

농도

~1 mg/mL

기술

ELISA: 1:20000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... KRT17(3872)

관련 카테고리

일반 설명

Anti-Keratin 17 antibody detects endogenous levels of total Keratin 17 protein.
Keratin 17/cytokeratin 17 (CK17) is a basal/myoepithelial cell keratin. It is expressed in the respiratory tract, urinary tract and various glands. CK17 is a member of the acidic type I CK family. It is mapped to human chromosome 17q21.

면역원

The antiserum was produced against synthesized peptide derived from human Keratin 17.

Immunogen Range: 381-430

애플리케이션

Anti-Keratin 17, C-Terminal antibody has been used in immunohistochemical staining.

생화학적/생리학적 작용

Keratin 17/cytokeratin 17 (CK17) plays a major role in the development of various human malignancies. It acts as a biomarker in endocervical glandular neoplasia. CK17 is involved in the development of cell and sizing of keratinocytes.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Pachyonychia Congenita
Smith FJD, et al.
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PAR2 regulates regeneration, transdifferentiation, and death
Piran R, et al.
Cell Death & Disease, 7(11), e2452-e2452 (2016)
Overexpression of cytokeratin 17 is associated with the development of papillary thyroid carcinoma and the presence of lymph node metastasis
Kim HS, et al.
International Journal of Clinical and Experimental Pathology, 8(5), 5695-5695 (2015)
Keratin 17 Is a Prognostic Biomarker in Endocervical Glandular Neoplasia
Mockler D, et al.
American Journal of Clinical Pathology, 148(3), 264-273 (2017)
Ron Piran et al.
Cell death & disease, 7(11), e2452-e2452 (2016-11-04)
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