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Merck
모든 사진(2)

주요 문서

SAB4501330

Sigma-Aldrich

Anti-GSK3 antibody produced in rabbit

affinity isolated antibody

동의어(들):

Factor A, GSK-3 α, GSK3-α, Glycogen synthase kinase-3 α, kinase GSK3-α

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

분자량

antigen 50 kDa

종 반응성

mouse, human, rat

농도

~1 mg/mL

기술

ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... GSK3A(2931)

일반 설명

GSK3A (glycogen synthase kinase 3 α) is a multifunctional protein serine kinase, that is mapped to human chromosome 19q13.

면역원

The antiserum was produced against synthesized peptide derived from human GSK3 alpha/beta.

Immunogen Range: 246-295

생화학적/생리학적 작용

GSK3A (glycogen synthase kinase 3 α) controls multiplication, migration and cell death. It participates in the WNT and PI3K (phosphoinositide 3-kinase) signalling pathways. This protein also modulates glucose levels, inflammation and immune responses.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Population-based linkage analysis of schizophrenia and bipolar case-control cohorts identifies a potential susceptibility locus on 19q13
Francks C, et al.
Molecular Psychiatry, 15(3), 319-325 (2010)
Theodore Lemuel Mathuram et al.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 36(4), 321-344 (2018-02-13)
This study aims to unravel the use of GSK-3 inhibitors as viable apoptotic inducers for teratocarcinoma-derived ovarian PA-1 cells. MTT assay was carried out to assess inhibitory concentrations of LiCl and TDG. AO/EB staining and Hoechst 33258 staining were employed
Vladimirs Pilipenko et al.
European journal of pharmacology, 881, 173290-173290 (2020-06-25)
The earliest hallmarks of sporadic Alzheimer's disease (sAD) are impaired glucose metabolism, chronic neuroinflammation, diminished synaptic plasticity and subsequent cognitive decline. The safest antidiabetic drug metformin has shown both glucose metabolism-improving and cognition-enhancing action in type 2 diabetes patients and
Zhuo Yu et al.
Gut, 63(11), 1793-1804 (2014-01-21)
Androgen receptor (AR) signalling contributes to male predominance in hepatocellular carcinoma (HCC), which is more pronounced in HBV-endemic areas. Cell cycle-related kinase (CCRK) is essential for AR-induced hepatocarcinogenesis but its molecular function in HBV-associated HCC remains obscure. To determine the
Rahul Bhattacharjee et al.
Biology of reproduction, 92(3), 65-65 (2015-01-09)
The signaling enzyme glycogen synthase kinase 3 (GSK3) exists as two isoforms-GSK3A and GSK3B. Protein phosphorylation by GSK3 has important signaling roles in several cells. In our past work, we found that both isoforms of GSK3 are present in mouse

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