SAB4501174

Anti-Connexin 43 antibody produced in rabbit

affinity isolated antibody

• 동의어(들): CX43, CXA1, CXN-43, Connexin 43, Gap junction 43 kDa heart protein
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: antigen 43 kDa
• 종 반응성: mouse, human, rat
• 농도: ~1 mg/mL
• 기술: ELISA: 1:20000; western blot: 1:500-1:1000
• NCBI 수납 번호: P17302
• UniProt 수납 번호: P17302
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... GJA1(2697)

설명

일반 설명

Connexin 43 belongs to the connexin protein family that forms gap junction. This protein is highly expressed in neurons and radial glia during development and in astrocytes in adult brains.

Connexin 43 belongs to the connexin protein family that forms gap junction. This protein is highly expressed in neurons and radial glia during development and in astrocytes in adult brains.

면역원

The antiserum was produced against synthesized peptide derived from human Connexin 43.

Immunogen Range: 332-381

애플리케이션

Anti-Connexin 43, C-Terminal antibody produced in rabbit has been used in flow cytometry.

생화학적/생리학적 작용

In rodents, connexin-43 (Cx-43) shows specific temporal patterns of expression during brain development. Experimental studies reveal that, connexin-43 expression increases in the brain during sheep ontogenesis.This protein might play a crucial role in neuronal migration as it resides in radial glial fibers which are closely associated with migrating neurons. It is also involved in transmembrane NAD⁺ transport. connexin-43, which is an element of gap junction, helps in cell–cell communication. Cx-43 is known to induce [Ca^2+] i burst phenomenon in uterine artery endothelial cells (UAECs).

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable