SAB4501145
Anti-LATS1 antibody produced in rabbit
affinity isolated antibody
동의어(들):
Kinase phosphorylated during mitosis protein, Large tumor suppressor homolog 1, Serine/threonine-protein kinase kpm, WARTS protein kinase, h-warts/ Large tumor suppressor homolog 2
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모든 사진(1)
About This Item
UNSPSC 코드:
12352203
NACRES:
NA.41
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
antigen 126 kDa
종 반응성
human, mouse
농도
~1 mg/mL
기술
ELISA: 1:40000
immunohistochemistry: 1:50-1:100
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... LATS1(9113)
일반 설명
Anti-LATS1 Antibody detects endogenous levels of total LATS1 protein.
The LATS1 (large tumor suppressor kinase 1) gene encodes a serine/threonine kinase and is located on human chromosome 6q24-25. It is present in the mitotic apparatus. It is also called as WARTS.
면역원
The antiserum was produced against synthesized peptide derived from human LATS1/2.
Immunogen Range: 1041-1090
Immunogen Range: 1041-1090
생화학적/생리학적 작용
The LATS1 (large tumor suppressor kinase 1) protein repress the multiplication and invasion of cervical cancer. It acts as a cell cycle inhibitor. Low level expression of LATS1 is associated with the progression and prognosis of glioma. It is a tumor suppressor gene, thereby it participates in various mitotic processes.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Decreased expression of LATS1 is correlated with the progression and prognosis of glioma
Ji T, et al.
Journal of Experimental & Clinical Cancer Research (2012)
Underexpression of LATS1 TSG in colorectal cancer is associated with promoter hypermethylation
Wierzbicki PM, et al.
World Journal of Gastroenterology, 19(27), 4363-4373 (2013)
LATS1 suppresses proliferation and invasion of cervical cancer
Deng J, et al.
Molecular Medicine Reports, 15(4), 1654-1660 (2017)
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