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Merck
모든 사진(2)

주요 문서

SAB4501126

Sigma-Aldrich

Anti-GATA3 antibody produced in rabbit

affinity isolated antibody

동의어(들):

GATA-binding factor 3, Trans-acting T-cell specific transcription factor GATA-3

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

분자량

antigen 47 kDa

종 반응성

human, mouse

농도

~1 mg/mL

기술

ELISA: 1:1000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... GATA3(2625)

관련 카테고리

일반 설명

Anti-GATA3 antibody detects endogenous levels of total GATA3 protein.
GATA-3 (GATA binding protein 3) is a T-cell transcription factor. It is highly expressed in fetal and adult thymus. It is located on human chromosome 10p14.

면역원

The antiserum was produced against synthesized peptide derived from human GATA3.

Immunogen Range: 274-323

생화학적/생리학적 작용

GATA-3 (GATA binding protein 3) plays an important role in the growth of T-cell neoplasms and early growth of T-cells. It acts as a specific marker in breast and urothelial carcinomas. GATA3 also acts as an immunophenotypic marker of acute leukemias.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

T-cell transcription factor GATA-3 is an immunophenotypic marker of acute leukemias with T-cell differentiation
Dorfman DM, et al.
Human Pathology, 65, 166-174 (2017)
Characterisation of GATA3 expression in invasive breast cancer: differences in histological subtypes and immunohistochemically defined molecular subtypes
Shaoxian T, et al.
Journal of Clinical Pathology (2017)
A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3)
Enciso-Mora V, et al.
Nature Genetics (2010)
Nazneen Fatima et al.
Human pathology, 45(8), 1625-1629 (2014-05-16)
The current available data on GATA-binding protein 3 (GATA3) expression in sarcomatoid urothelial carcinoma are limited, especially in the non-tissue microarray-based setting. In this study, we analyzed the expression of GATA3 in sarcomatoid urothelial carcinoma of the bladder in cystectomy/cystoprostatectomy

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