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Merck
모든 사진(3)

주요 문서

SAB4500548

Sigma-Aldrich

Anti-Adrenergic Receptor α-2A antibody produced in rabbit

affinity isolated antibody

동의어(들):

α-2 adrenergic receptor subtype C10, α-2A adrenergic receptor, α-2A adrenoceptor, α-2A adrenoreceptor, α-2AAR

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

분자량

antigen 48 kDa

종 반응성

mouse, human, rat

농도

~1 mg/mL

기술

ELISA: 1:20000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... ADRA2A(150)

일반 설명

ADRA2A (α-2A adrenergic receptor gene) is located on human chromosome 10q25. It is expressed in the caudate nucleus.
Anti-Adrenergic Receptor α-2A Antibody detects endogenous levels of total Adrenergic Receptor α-2A protein.

면역원

The antiserum was produced against synthesized peptide derived from human Adrenergic Receptor alpha-2A.

Immunogen Range: 331-380

생화학적/생리학적 작용

ADRA2A (α-2A adrenergic receptor gene) plays an important role in irritability, impulsivity, aggression and memory traits. Mutations in ADRA2A affects the liberation of insulin and glucose regulation. Variations in ADRA2A is linked with poor clinical prognostication. It participates in autism spectrum disorders (ASDs).

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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Lot/Batch Number

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문서 라이브러리 방문

ADRA2A Germline Gene Polymorphism is Associated to the Severity, but not to the Risk, of Breast Cancer
Kaabi B, et al.
Pathology Oncology Research, 22(2), 357-365 (2016)
Association between the adrenergic alpha 2A receptor gene (ADRA2A) and measures of irritability, hostility, impulsivity and memory in normal subjects
Comings DE, et al.
Psychiatric Genetics, 10(1), 39-42 (2000)
Alpha2A adrenergic receptor genetic variation contributes to hyperglycemia after myocardial infarction
Adefurin A, et al.
International Journal of Cardiology, 215, 482-486 (2016)
Replication of genome-wide association studies (GWAS) loci for fasting plasma glucose in African-Americans
Ramos E, et al.
Diabetologia, 54(4), 783-788 (2011)
Abhishek Tripathi et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(13), E1659-E1668 (2015-03-17)
Recent evidence suggests that chemokine (C-X-C motif) receptor 4 (CXCR4) contributes to the regulation of blood pressure through interactions with α1-adrenergic receptors (ARs) in vascular smooth muscle. The underlying molecular mechanisms, however, are unknown. Using proximity ligation assays to visualize

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