SAB4500418

Anti-GPR151 antibody produced in rabbit

affinity isolated antibody

• 동의어(들): G-protein coupled receptor PGR7, GPCR-2037, GPR151, PGR7, Probable G-protein coupled receptor 151
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: antigen 46 kDa
• 종 반응성: rat, human, mouse
• 농도: ~1 mg/mL
• 기술: ELISA: 1:1000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• NCBI 수납 번호: Q8TDV0
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... GPR151(134391)

설명

일반 설명

G protein-coupled receptor 151 (GPR151) is encoded by the gene mapped to human chromosome 5. It belongs to the A type of G protein-coupled receptor (GPCR) family and it shows homology with galanin receptor 2 and 3. In mice, GPR151 transcript is highly and specifically expressed in habenular neurons.

면역원

The antiserum was produced against synthesized peptide derived from human GPR151.

Immunogen Range: 370-419

애플리케이션

Anti-GPR151, C-Terminal antibody produced in rabbit has been used for Western blotting.

생화학적/생리학적 작용

G protein-coupled receptor 151 (GPR151) is a highly conserved protein, and acts as a potential target for psychiatric drug development, due to its expression in habenular neurons which may be critically involved in the pathophysiology of psychiatric disorders such as addiction and depression. Experimental studies reveal that GPR151 might play a neuroprotective and/or pro-regenerative role in the dorsal root ganglion (DRG) after nerve injury.

특징 및 장점

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물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable