SAB4500007

Anti-AKT1 antibody produced in rabbit

affinity isolated antibody

• 동의어(들): C-AKT/ RAC-PK-β, PKB, Protein kinase Akt-2, Protein kinase B, RAC-PK-α
• MDL number: MFCD01322594
• UNSPSC 코드: 12352203
• NACRES: NA.41
• 결합: unconjugated
• application: ELISA; IHC; WB
• 클론: polyclonal
• 종 반응성: mouse, rat, human
• citations: 3
• 기술: ELISA: 1:40000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: antigen 55 kDa
• 종 반응성: mouse, rat, human
• 농도: ~1 mg/mL
• 기술: ELISA: 1:40000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI 수납 번호: P31749
• UniProt 수납 번호: P31749
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... AKT1(207)

설명

일반 설명

The AKT1 (AKT serine/threonine kinase 1) gene is also called as v-akt murine thymoma viral oncogene homolog 1 and PKBα (protein kinase B). It is upregulated in liver, muscle and adipocytes. AKT1 gene is mapped to human chromosome 14q32. It is a member of AKT family that has an amino-terminal pleckstrin homology (PH) domain, a short α-helical linker and a carboxyl-terminal kinase domain.

Anti-AKT1 Antibody detects endogenous levels of total AKT1 protein.

면역원

The antiserum was produced against synthesized peptide derived from human AKT1/2/3.

Immunogen Range: 281-330

생화학적/생리학적 작용

The protein encoded by AKT1 (AKT serine/threonine kinase 1) gene controls the survival of cell and anti-apoptotic actions that attack the pathogenesis of several cancers, hence it plays a crucial role in tumorigenesis. In mice, AKT1 is essential for normal development.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable