SAB4300637

Anti-FGFR4 antibody produced in rabbit

affinity isolated antibody

• 동의어(들): Anti-CD334, Anti-JTK2, Anti-MGC20292, Anti-TKF
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: ~110 kDa
• 종 반응성: human, rat
• 농도: 1 mg/mL
• 기술: western blot: 1:500-1:1000
• 동형: IgG
• 면역원 서열: (L-T-V-A-L)
• NCBI 수납 번호: NM_002011.3
• UniProt 수납 번호: P22455
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... FGFR4(2264)

설명

일반 설명

FGFR4 (fibroblast growth factor receptor 4) belongs to FGFR kinase family. In adult tissues, FGFR is expressed in a cell type-specific mode. It is located on chromosome 5q35.

The antibody detects endogenous level of total FGFR4 protein.

면역원

Peptide sequence around aa. 45-49 ( L-T-V-A-L), according to the protein NP_002002.3

생화학적/생리학적 작용

Aberrations in FGFR4 results in neuroblastoma and altered receptor degradation. It acts as a predictive biomarker in oral and oropharyngeal squamous cell carcinoma. Suppressing FGFR4 may affect the biological characteristics in gastric cancer cells.

특징 및 장점

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표적 설명

Receptor for acidic fibroblast growth factor. Does not bind to basic fibroblast growth factor. Binds FGF19.

물리적 형태

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable