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Merck
모든 사진(2)

Key Documents

SAB4300580

Sigma-Aldrich

Anti-ERBB3 (Ab-1328) antibody produced in rabbit

affinity isolated antibody

동의어(들):

Anti-ErbB-3 antibody produced in rabbit, Anti-HER3 antibody produced in rabbit, Anti-LCCS2 antibody produced in rabbit, Anti-MDA-BF-1 antibody produced in rabbit, Anti-v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) antibody produced in rabbit

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

분자량

~185 kDa

종 반응성

human, mouse, rat

농도

1 mg/mL

기술

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000

동형

IgG

면역원 서열

(P-D-Y-W-H)

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... ERBB3(2065)

면역원

Peptide sequence around aa. 1326-1330 (P-D-Y-W-H), according to the protein ERBB3.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

표적 설명

Binds and is activated by neuregulins and NTAK.

물리적 형태

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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International journal of oncology, 45(4), 1583-1593 (2014-07-16)
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Cancer science, 105(7), 779-787 (2014-04-24)
Human epidermal growth factor receptor 2 (HER2)-positive breast cancer is treated with HER2-targeted agents, such as trastuzumab and lapatinib, that suppress signaling by phosphatidylinositol 3-kinase (PI3K)-Akt and MAPK pathways. However, resistance to HER2-targeted therapy remains a major clinical problem. Overexpression

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