SAB4300230

Anti-phospho-EIF2AK2 (pThr⁴⁵¹) antibody produced in rabbit

affinity isolated antibody

• 동의어(들): Anti-EIF2AK1 antibody produced in rabbit, Anti-MGC126524 antibody produced in rabbit, Anti-PKR antibody produced in rabbit, Anti-PRKR antibody produced in rabbit, Anti-eukaryotic translation initiation factor 2-alpha kinase 2 antibody produced in rabbit
• MDL number: MFCD03455796
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: ~74 kDa
• 종 반응성: human
• 농도: 1 mg/mL
• 기술: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
• 동형: IgG
• 면역원 서열: (K-G-TP-L-R)
• NCBI 수납 번호: NP_001129123.1
• UniProt 수납 번호: P19525
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pThr451)
• 유전자 정보: human ... EIF2AK2(5610)

설명

면역원

Peptide sequence around phosphorylation site of threonine 451 (K-G-T(p)-L-R), according to the protein EIF2AK2.

특징 및 장점

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표적 설명

Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.

물리적 형태

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable