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Merck
모든 사진(3)

Key Documents

SAB4300084

Sigma-Aldrich

Anti-phospho-RPS6KA1 (pThr348) antibody produced in rabbit

affinity isolated antibody

동의어(들):

Anti-HU-1 antibody produced in rabbit, Anti-MAPKAPK1A antibody produced in rabbit, Anti-RSK antibody produced in rabbit, Anti-RSK1 antibody produced in rabbit, Anti-ribosomal protein S6 kinase, 90kDa, polypeptide 1 antibody produced in rabbit

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

분자량

~90 kDa

종 반응성

mouse, rat, human

농도

1 mg/mL

기술

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000

동형

IgG

면역원 서열

(S-R-TP-P-R)

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

phosphorylation (pThr348)

유전자 정보

human ... RPS6KA1(6195)

면역원

Peptide sequence around phosphorylation site of threonine 348 (S-R-T(p)-P-R), according to the protein RPS6KA1.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

표적 설명

Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.

물리적 형태

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Rong-Yu Liu et al.
Scientific reports, 10(1), 608-608 (2020-01-19)
Multiple kinases converge on the transcription factor cAMP response element-binding protein (CREB) to enhance the expression of proteins essential for long-term synaptic plasticity and memory. The p90 ribosomal S6 kinase (RSK) is one of these kinases, although its role is
Irem Ozkan-Dagliyan et al.
Cell reports, 31(11), 107764-107764 (2020-06-20)
We address whether combinations with a pan-RAF inhibitor (RAFi) would be effective in KRAS mutant pancreatic ductal adenocarcinoma (PDAC). Chemical library and CRISPR genetic screens identify combinations causing apoptotic anti-tumor activity. The most potent combination, concurrent inhibition of RAF (RAFi)
B Nadratowska-Wesolowska et al.
Oncogene, 33(40), 4823-4836 (2013-10-22)
FGFR1 (fibroblast growth factor receptor 1) regulates many key cellular responses including proliferation, migration and differentiation through activation of signaling pathways. Irregularities in FGFR1 signaling have been implicated in several pathological conditions, including human cancer. In order to discover novel

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