생물학적 소스
mouse
Quality Level
항체 형태
purified from hybridoma cell culture
항체 생산 유형
primary antibodies
클론
HG-36, monoclonal
형태
buffered aqueous solution
종 반응성
human
포장
antibody small pack of 25 μL
농도
~1.0 mg/mL
기술
ELISA: 0.2-0.4 μg/mL using 10 μg/ml human haptoglobin for coating
dot blot: suitable
immunoblotting: suitable
immunoprecipitation (IP): suitable
동형
IgG1
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... HP(3240)
일반 설명
Haptoglobin, also known as HP, is a serum α2-glycoprotein that exists as a tetramer, composed of two smaller identical alpha (α) chains and two larger identical beta (β) chains. The α-chains are linked to each other by a disulfide bond and each β-chain is similarly linked to an α-chain.
Monoclonal Anti-Haptoglobin specifically recognizes the three types of human haptoglobin (types 1-1, 2-1, and 2-2) The antibody recognizes both purified and haptoglobin in human serum, and shows no crossreactivity with human IgG, transferrin, C-reactive protein, α-1-acid glycoprotein, albumin, hemoglobin, or bovine, goat and sheep serum haptoglobin.
Monoclonal Anti-Haptoglobin specifically recognizes the three types of human haptoglobin (types 1-1, 2-1, and 2-2) The antibody recognizes both purified and haptoglobin in human serum, and shows no crossreactivity with human IgG, transferrin, C-reactive protein, α-1-acid glycoprotein, albumin, hemoglobin, or bovine, goat and sheep serum haptoglobin.
면역원
purified haptoglobin from pooled human plasma
애플리케이션
The antibody is recommended to use in various immunological techniques, including ELISA, dot blot, immunoprecipitation, and immunoblot . The antibody reacts against native and denatured (non-reduced) human haptoglobin but does not recognize the haptoglobin under reducing conditions.
물리적 형태
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative.
기타 정보
This product is for R&D use only, not for drug, household, or other uses.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Alessio Fasano
Physiological reviews, 91(1), 151-175 (2011-01-21)
The primary functions of the gastrointestinal tract have traditionally been perceived to be limited to the digestion and absorption of nutrients and to electrolytes and water homeostasis. A more attentive analysis of the anatomic and functional arrangement of the gastrointestinal
Kati Mokkala et al.
Metabolism: clinical and experimental, 69, 43-50 (2017-03-14)
Increased intestinal permeability with subsequent metabolic endotoxemia, i.e., elevated circulating levels of bacterial lipopolysaccharide, LPS, has been introduced as a novel initiator of obesity related metabolic disturbances in non-pregnant individuals. The objective was to investigate the extent to which intestinal
Haptoglobin: the evolutionary product of duplication, unequal crossing over, and point mutation.
B H Bowman et al.
Advances in human genetics, 12, 189-261 (1982-01-01)
S M Hossein Sadrzadeh et al.
American journal of clinical pathology, 121 Suppl, S97-104 (2004-08-10)
Haptoglobin is a positive acute phase protein that binds free hemoglobin and removes it from the circulation to prevent kidney injury, and iron lossfollowing hemolysis. Also, by bindingfree hemoglobin, haptoglobin functions as an antioxidant. In addition, haptoglobin acts as a
C J Chen et al.
Infection and immunity, 64(12), 5008-5014 (1996-12-01)
The majority of in vitro-grown Neisseria gonorrhoeae strains were unable to use hemoglobin as the sole source of iron for growth (Hgb-), but a minor population was able to do so (Hgb+). The ability of Hgb+ gonococci to utilize hemoglobin
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