추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
GG-7, monoclonal
형태
buffered aqueous solution
종 반응성
human
농도
~1 mg/mL
기술
ELISA: suitable
immunofluorescence: suitable
indirect ELISA: 0.25-0.5 μg/mL using 5μg/mL human IgG for coating.
동형
IgG1
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
일반 설명
Monoclonal Anti-Human IgG (Fc specific) (mouse IgG1 isotype) is derived from the GG-7 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from mouse immunized with Purified human IgG myeloma proteins covalently coupled to polyaminostyrene (PAS) microbeads. IgGs are the most common Immunoglobulins isotype in blood, lymph fluid, cerebrospinal fluid, and peritoneal fluid. IgGs include four subclasses (IgG1, IgG2, IgG3, and IgG4), they consist of a variable Fab fragment (which includes the antibody recognition site), and a conserved Fc fragment.
면역원
Purified human IgG myeloma proteins covalently coupled to polyaminostyrene (PAS) microbeads
애플리케이션
Monoclonal Anti-Human IgG (Fc specific) antibody has been used in:
- ELISA
- Imprint Immunofixation (IIF)
- Immunofluorometric Assay (IFMA)
- Hemagglutination (HA)
- Hemagglutination Inhibition (HAI)
- Particle Counting Immunoassay (PACIA)
- detection of cytoplasmic IgG
생화학적/생리학적 작용
The crystallizable fragment (Fc) of IgG has various important functions such as complement fixation, site for rheumatoid factor (autoantibody directed to Fc) attachment, passage through the placental membrane and protein A binding. IgG deficiencies are often associated with various diseases.
물리적 형태
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
Jefferis R., et al.,
Annales De Biologie Clinique, 52, 57-65 (1994)
Wang L., et al.,
Hybridoma, 1, 293-302 (1982)
Papadea C. and Check IJ.
Critical Reviews in Clinical Laboratory Sciences, 27, 27-58 (1989)
Structure and function of human and murine receptors for IgG
Unkeless J C, et al.
Annual Review of Immunology, 6(1), 251-281 (1988)
C B Reimer et al.
Hybridoma, 3(3), 263-275 (1984-01-01)
Stable clones of 31 mouse hybridomas that produce monoclonal antibodies (MAbs) against human IgG antigenic determinants were obtained. The number of hybridomas of different specificity described are: 2 anti-IgG1 Fc, 1 anti-IgG2 Fc, 1 anti-IgG2 Fd, 2 anti-IgG3 Fc, 2
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