SAB4200471

Anti-SND1 (C-terminal) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• 동의어(들): Anti-TDRD11, Anti-staphylococcal nuclease and tudor domain containing 1, p100
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: antigen ~102 kDa
• 종 반응성: rat, mouse, human
• 농도: ~1.0 mg/mL
• 기술: immunoprecipitation (IP): 1-2 μg using lysates of rat NRK cells.; indirect immunofluorescence: 2.5-5.0 μg/mL using human HeLa cells; western blot: 0.25-0.5 μg/mL using whole extracts of mouse NIH-3T3 cells.
• UniProt 수납 번호: Q7KZF4
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... SND1(27044) ; mouse ... Snd1(56463) ; rat ... Snd1(64635)

설명

일반 설명

Staphylococcal nuclease and tudor domain containing 1 (SND1) protein contains five staphylococcal nuclease-like domains and a tudor-like domain. SND1 is a component of the RNA-induced silencing complex (RISC). This gene is highly conserved from yeast to human.

면역원

peptide corresponding to the C-terminal region of human SND1 (GeneID: 27044), conjugated to KLH. The corresponding sequence is identical in mouse and rat.

애플리케이션

Anti-SND1 (C-terminal) antibody produced in rabbit has been used in immunoblotting, immunoprecipitation and immunofluorescence.

생화학적/생리학적 작용

Staphylococcal nuclease and tudor domain containing 1 (SND1) has been shown to be involved in the regulation of transcription and RNA biogenesis. It is known to interact with nucleic acids and proteins. SND1 promotes the breakdown of hyper-edited inosine-containing miRNA precursors. It modulates miRNA transcription and translation through RNA editing by ADAR (adenosine deaminase acting on RNA). Increased SND1 expression is seen in human colon cancer tissues and cell lines.

물리적 형태

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable