추천 제품
생물학적 소스
mouse
결합
unconjugated
항체 형태
tissue culture supernatant
항체 생산 유형
primary antibodies
클론
CAV1, monoclonal
형태
buffered aqueous solution
분자량
antigen 22 kDa
종 반응성
rat, human, mouse
향상된 검증
independent
Learn more about Antibody Enhanced Validation
기술
immunohistochemistry: suitable
indirect immunofluorescence: 1:1000-1:2000 using human HUVEC or mouse 3T3 cells.
western blot: suitable
동형
IgM
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... CAV1(857)
mouse ... Cav1(12389)
rat ... Cav1(25404)
일반 설명
Caveolin-1 (CAV1) is a multifunctional scaffolding protein, that has three exons. It is located on human chromosome 7q31.
면역원
synthetic peptide corresponding to a sequence at the N-terminal of human caveolin-1, conjugated to KLH.
애플리케이션
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
Monoclonal Anti-Caveolin-1 antibody has been used in western blot analysis.
생화학적/생리학적 작용
Caveolin-1 may play a major role in the growth and evolution of cancer. It participates in glucose metabolism. It may also participate in angiogenesis. Cav-1 helps to control the expression of glucose transporters.
물리적 형태
Culture supernatant solution containing 15 mM sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Ye Xiong et al.
Oncotarget, 8(15), 24902-24914 (2017-02-18)
As the most prevalent primary brain tumor, gliomas are highly metastatic, invasive and are characteristic of high levels of glial cell-line derived neurotrophic factor (GDNF). GDNF is an important factor for invasive glioma cell growth; however, the underlying mechanism involved
Expression of flotilin-2 and acrosome biogenesis are regulated by MiR-124 during spermatogenesis
Wu Y, et al.
PLoS ONE, 10(8), e0136671-e0136671 (2015)
Margaret E Tome et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 38(12), 2209-2222 (2018-10-23)
P-glycoprotein (PgP) is the major drug efflux pump in human cerebral microvessels. PgP prevents pathogens, toxins and therapeutic drugs from entering the CNS. Understanding the molecular regulation of PgP activity will suggest novel mechanisms to improve CNS drug delivery. Previously
Adam C Midgley et al.
The Journal of biological chemistry, 290(18), 11218-11234 (2015-02-27)
Hyaluronan (HA) promotes transforming growth factor (TGF)-β1-driven myofibroblast phenotype. However, HA can also have disease-limiting activity. Bone morphogenetic protein-7 (BMP7) is an antifibrotic cytokine that antagonizes TGF-β1, and isolated studies have demonstrated that HA can both mediate and modulate BMP7
Estrogen insensitivity in a model of estrogen receptor positive breast cancer lymph node metastasis.
Joshua Chuck Harrell et al.
Cancer research, 67(21), 10582-10591 (2007-11-03)
The lymphatic system is a common avenue for the spread of breast cancer cells and dissemination through it occurs at least as frequently as hematogenous metastasis. Approximately 75% of primary breast cancers are estrogen receptor (ER) positive and the majority
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