추천 제품
생물학적 소스
rabbit
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
분자량
41 kDa
종 반응성
human, rat, mouse
농도
1 mg/mL
기술
ELISA: suitable
western blot: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... NKX2-1(7080)
일반 설명
NK2 homeobox 1 (NKX2-1) is expressed in epithelial cells of the thyroid gland and lungs. The gene encoding NKX2-1 is localized on human chromosome 14q13.
면역원
Antibody was raised against a 16 amino acid peptide near the amino terminus of human NKX2-1.
생화학적/생리학적 작용
NK2 homeobox 1(NKX2-1) has a role in the development of thyroid glands, lungs and brain. It modulates gene expression during embryogenesis. NKX2-1 has been found to be expressed in adenocarcinoma and small cell lung cancer. This protein acts as an immunohistological marker to distinguish between primary lung carcinoma and non-pulmonary cancer.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
결합
The action of this antibody can be blocked using blocking peptide SBP3500757.
물리적 형태
Supplied at 1 mg/mL in PBS with 0.02% sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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관련 제품
Storage Class Code
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Value of thyroid transcription factor (TTF)-1 for diagnosis and prognosis of patients with locally advanced or metastatic small cell lung cancer.
Misch D, et al.
Diagnostic Pathology, 10(1), 21-21 (2015)
Expression of thyroid transcription factor-1 is associated with a basal-like phenotype in breast carcinomas.
Klingen T A, et al.
Diagnostic Pathology, 8(1), 80-80 (2013)
Recurrent drop attacks in early childhood as presenting symptom of benign hereditary chorea caused by TITF1 gene mutations.
Rosati A, et al.
Developmental Medicine and Child Neurology, 57(8), 777-779 (2015)
Benign hereditary chorea related to NKX2. 1: expansion of the genotypic and phenotypic spectrum.
Peall K J, et al.
Developmental Medicine and Child Neurology, 56(7), 642-648 (2014)
Distinct expression of NK2 homeobox 1 (NKX2-1) and goblet cell hyperplasia in nasal polyps with different endotypes.
Du J, et al.
International Forum of Allergy & Rhinology, 7(7) (2017)
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