SAB3500048

Anti-SCARB1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 동의어(들): Anti-CD36 and LIMPII analog, Anti-CD36 antigen-like 1, Anti-CLA-1, Anti-SR-BI, Anti-SRB1, Anti-Scavenger receptor class B member 1
• MDL number: MFCD01634166
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 종 반응성: human, mouse, rat
• 기술: ELISA: suitable; immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• NCBI 수납 번호: Q8WTV0
• UniProt 수납 번호: Q8WTV0
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... SCARB1(949)

설명

일반 설명

Scavenger receptor class B member 1 (SCARB1), also known as SR-BI, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARB1 is a multi-ligand cell-surface receptor that mediates the selective uptake of lipid from HDL cholesterol into cells and is expressed in steroidogenic tissues in adult animals. Other ligands of SCARB1 include native, acetylated, or oxidized LDL and anionic phospholipids. SCARB1-deficient mice have elevated HDL levels and increased susceptibility to atherosclerosis on fat feeding, indicating its importance in the regulation of cholesterol homeostasis. Along with CLDN1, LDL-R, and the tetraspanin superfamily member CD81, SCARB1 has been reported to be an entry factor for the Hepatitis C virus. At least two isoforms of SCARB1 are known to exist.

면역원

SCARB1 antibody was raised against a 15 amino acid peptide near the amino terminus of human SCARB1.

애플리케이션

Anti-SCARB1 antibody produced in rabbit has been used for immunohistochemistry.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

결합

The action of this antibody can be blocked using blocking peptide SBP3500048.

물리적 형태

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable