SAB3500023

Anti-TUBA1A (TUBA3) Antibody

chicken polyclonal

• 동의어(들): Anti-LIS3, Anti-TUBA1A, Anti-TUBA3, Anti-Tubulin alpha-1A
• MDL number: MFCD00145891
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 제품명: Anti-α-Tubulin from chicken, affinity isolated antibody, buffered aqueous solution
• 생물학적 소스: chicken
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 종 반응성: rat, human, mouse
• 기술: indirect ELISA: suitable; western blot: suitable
• NCBI 수납 번호: CAA25855
• UniProt 수납 번호: Q13748
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... TUBA1A(7846)

설명

일반 설명

Tubulin α 1A (TUBA1A) is a member of α-tubulin gene family. It is encoded by the gene mapped to human chromosome 12q13.12. Tubulin α 1A is a vital structural subunit of microtubules that are temporarily expressed in almost all post-mitotic neurons during neuronal development. The encoded protein structure contains a core of two β-sheets enclosed by α-helices. TUBA1A is characterized with an amino-terminal domain having guanine nucleotide-binding region, an intermediate domain and a carboxy-terminal domain.

면역원

Tubulin antibody was raised against a 16 amino acid peptide near the amino terminus of human Tubulin.

애플리케이션

Anti-α-tubulin from chicken has been used for Western blotting and immunohistochemistry.

생화학적/생리학적 작용

Gene mutation of tubulin α-1A (TUBA1A) is observed in perisylvian asymmetrical polymicrogyria, polymicrogyria-like cortical dysplasia, and microlissencephaly in fetal cases. Alteration in the expression of the gene impairs neural migration and causes lissencephaly (LIS).

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

결합

The action of this antibody can be blocked using blocking peptide SBP3500023.

물리적 형태

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable