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Merck
모든 사진(1)

주요 문서

SAB2501472

Sigma-Aldrich

Anti-SLC2A4 (C-terminal) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

동의어(들):

Anti-GLUT4, Glucose transporter 4, Insulin-responsive glucose transporter type 4, Solute carrier family 2 (facilitated glucose transporter), member 4

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

goat

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

종 반응성

rat, mouse, human, bovine

기술

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... SLC2A4(6517)

일반 설명

Solute carrier family 2 member 4 (SLC2A4) is also known as glucose transporter-4 (GLUT4). It is highly expressed in adipose tissue and skeletal muscles. The gene encoding SLC2A4 is localized on human chromosome 17p13.

면역원

Peptide with sequence TELEYLGPDEND, from the C-terminal region of the protein sequence according to NP_001033.1

생화학적/생리학적 작용

Solute carrier family 2 member 4 (SLC2A4) transports glucose into cells in response to insulin. Levels of this protein have been shown to be reduced in type 2 diabetes.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

G I Bell et al.
Diabetes, 38(8), 1072-1075 (1989-08-01)
Glucose uptake by heart, skeletal muscle, and adipose tissue is acutely regulated by insulin, which stimulates facilitative glucose transport, at least in part, by promoting the translocation of transporters from an intracellular pool to the plasma membrane. cDNAs encoding the
Malgorzata Malodobra-Mazur et al.
Gene, 576(1 Pt 3), 499-504 (2015-11-04)
The glucose uptake by numerous cells like adipocytes or skeletal muscle cells requires activation of specific proteins called glucose transporters. GLUT4 content and its activation as well as SLC2A4 gene expression level are decreased in patients with type 2 diabetes.
Wei-Feng Shan et al.
Journal of Zhejiang University. Science. B, 12(8), 677-682 (2011-07-29)
Decreased glucose tolerance and diabetes are frequently observed in advanced liver cirrhosis patients and may be related to insulin resistance. Glucose transporter-4 (GLUT4), one of the most important glucose transporters, plays a key role in the development of type 2

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