SAB2500826

Anti-Proopiomelanocortin/POMC antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• 동의어(들): Anti-ACTH, Anti-CLIP, Anti-POC
• MDL number: MFCD00162087
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: goat
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 종 반응성: mouse, human, rat
• 기술: immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• UniProt 수납 번호: P01189
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... POMC(5443)

설명

일반 설명

Proopiomelanocortin (POMC) is a pro-peptide and multifunctional precursor protein for melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone ACTH. The POMC gene is mapped to human chromosome 2p23.3. It is expressed in skin, pituitary gland, and tissues of the immune system.

면역원

Peptide with sequence C-NAIIKNAYKKGE from the C Terminus of the protein sequence according to NP_000930.1; NP_001030333.1.

생화학적/생리학적 작용

Proopiomelanocortin (POMC) expression is regulated by hypermethylation of the upstream CpG-rich island in the gene. Mutations in the POMC gene are implicated in adrenocorticotropic hormone (ACTH) deficiency. Adrenal insufficiency and obesity are correlated to loss of function mutations in POMC.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable