추천 제품
제품명
Anti-Choline acetyltransferase antibody produced in goat, affinity isolated antibody, buffered aqueous solution
생물학적 소스
goat
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
종 반응성
canine, chimpanzee, human, pig
기술
indirect ELISA: suitable
western blot: suitable
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... CHAT(1103)
일반 설명
Choline acetyltransferase (CHAT) has a molecular weight of about 68kDa. It is synthesized in the parakaryon and is transported to the axon terminals. CHAT is part of the choline/carnitine acyltransferase family.
면역원
Peptide with sequence CKEKATRPSQGHQP from the C Terminus of the protein sequence according to NP_065574; NP_066264; NP_066265; NP_066266.
생화학적/생리학적 작용
Choline acetyltransferase (CHAT) is involved in the synthesis of acetylcholine in neurons. It catalyzes the transfer of an acetyl group between acetyl-coenzyme A and choline. Mutations in the gene encoding this protein have been associated with congenital neuromuscular disorders.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Choline acetyltransferase structure reveals distribution of mutations that cause motor disorders
The Embo Journal (2004)
Blood pressure regulation by CD4+ lymphocytes expressing choline acetyltransferase.
Olofsson PS, e.al
Nature Biotechnology (2016)
Jessica A Ash et al.
Neurobiology of disease, 70, 32-42 (2014-06-17)
Down syndrome (DS) is marked by intellectual disability (ID) and early-onset of Alzheimer's disease (AD) neuropathology, including basal forebrain cholinergic neuron (BFCN) degeneration. The present study tested the hypothesis that maternal choline supplementation (MCS) improves spatial mapping and protects against
J J Roland et al.
Brain structure & function, 219(4), 1231-1237 (2014-06-27)
The medial septum and diagonal band of Broca (MSDB) influence hippocampal function through cholinergic, GABAergic, and glutamatergic septohippocampal neurons. Non-selective damage of the MSDB or intraseptal scopolamine impairs classical conditioning of the eyeblink response (CCER). Scopolamine preferentially inhibits GABAergic MSDB
Irene E Whitney et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(30), 10109-10121 (2014-07-25)
The retina contains two populations of cholinergic amacrine cells, one positioned in the ganglion cell layer (GCL) and the other in the inner nuclear layer (INL), that together comprise ∼1/2 of a percent of all retinal neurons. The present study
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