추천 제품
생물학적 소스
goat
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
종 반응성
human
기술
indirect ELISA: suitable
indirect immunofluorescence: suitable
western blot: suitable
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... ASPN(54829)
관련 카테고리
일반 설명
Asporin (ASPN) is an extracellular matrix (ECM) macromolecule. It is encoded by the gene mapped to human chromosome 9q22.31. ASPN is a member of small leucine-rich proteoglycan (SLRP) family.
면역원
Peptide with sequence C-IHENKVKKIQKDT from the internal region of the protein sequence according to NP_060150.3.
생화학적/생리학적 작용
Asporin (ASPN) plays a vital role in regulation of chondrogenesis and helps to maintain the cartilage matrix. ASPN also facilitates transforming growth factor (TGF)-f-mediated signaling. It stimulates osteoblast collagen mineralization by interacting with collagen and calcium. Mutation in the gene is associated with the development of acetabular dysplasia (AD) and hip osteoarthritis.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Copy number loss in the region of the ASPN gene in patients with acetabular dysplasia: ASPN CNV in acetabular dysplasia.
Bone & joint research, 6(7), 439-445 (2017)
Workshop Abstracts, 2(2), 163-163 (2005)
Asporin competes with decorin for collagen binding, binds calcium and promotes osteoblast collagen mineralization.
The Biochemical Journal, 423(1), 53-59 (2009)
The CALM1 core promoter polymorphism is not associated with hip osteoarthritis in a United Kingdom Caucasian population.
Osteoarthritis and Cartilage, 14(3), 295-298 (2006)
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