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Merck
모든 사진(2)

주요 문서

SAB2500127

Sigma-Aldrich

Anti-ASPORIN/ASPN antibody produced in goat

affinity isolated antibody, buffered aqueous solution

동의어(들):

Anti-Asporin (LRR class 1), Anti-FLJ20129, Anti-PLAP1, Anti-SLRR1C

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

goat

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

종 반응성

human

기술

indirect ELISA: suitable
indirect immunofluorescence: suitable
western blot: suitable

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... ASPN(54829)

관련 카테고리

일반 설명

Asporin (ASPN) is an extracellular matrix (ECM) macromolecule. It is encoded by the gene mapped to human chromosome 9q22.31. ASPN is a member of small leucine-rich proteoglycan (SLRP) family.

면역원

Peptide with sequence C-IHENKVKKIQKDT from the internal region of the protein sequence according to NP_060150.3.

생화학적/생리학적 작용

Asporin (ASPN) plays a vital role in regulation of chondrogenesis and helps to maintain the cartilage matrix. ASPN also facilitates transforming growth factor (TGF)-f-mediated signaling. It stimulates osteoblast collagen mineralization by interacting with collagen and calcium. Mutation in the gene is associated with the development of acetabular dysplasia (AD) and hip osteoarthritis.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Copy number loss in the region of the ASPN gene in patients with acetabular dysplasia: ASPN CNV in acetabular dysplasia.
Sekimoto T, et al.
Bone & joint research, 6(7), 439-445 (2017)
Workshop Abstracts, 2(2), 163-163 (2005)
Asporin competes with decorin for collagen binding, binds calcium and promotes osteoblast collagen mineralization.
Kalamajski S, et al.
The Biochemical Journal, 423(1), 53-59 (2009)
The CALM1 core promoter polymorphism is not associated with hip osteoarthritis in a United Kingdom Caucasian population.
Loughlin J, et al.
Osteoarthritis and Cartilage, 14(3), 295-298 (2006)

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