S9944
Sibutramine hydrochloride monohydrate
≥98% (HPLC), solid
동의어(들):
1-(4-Chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)cyclobutanemethanamine hydrochloride monohydrate, Meridia, Reductil
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모든 사진(3)
About This Item
실험식(Hill 표기법):
C17H26ClN · HCl
CAS Number:
Molecular Weight:
316.31
MDL number:
UNSPSC 코드:
12352116
PubChem Substance ID:
NACRES:
NA.77
추천 제품
Quality Level
분석
≥98% (HPLC)
양식
solid
약물 제어
USDEA Schedule IV
저장 조건
desiccated
색상
white
solubility
DMSO: >30 mg/mL
H2O: insoluble
주관자
Abbott
저장 온도
room temp
SMILES string
O.Cl.CC(C)CC(N(C)C)C1(CCC1)c2ccc(Cl)cc2
InChI
1S/C17H26ClN.ClH.H2O/c1-13(2)12-16(19(3)4)17(10-5-11-17)14-6-8-15(18)9-7-14;;/h6-9,13,16H,5,10-12H2,1-4H3;1H;1H2
InChI key
KFNNPQDSPLWLCX-UHFFFAOYSA-N
유전자 정보
human ... SLC6A2(6530) , SLC6A3(6531) , SLC6A4(6532)
유사한 제품을 찾으십니까? 방문 제품 비교 안내
애플리케이션
Sibutramine hydrochloride monohydrate was used as standard to screen dietary supplements for sibutramine using ion mobility spectrometer.1
생화학적/생리학적 작용
Sibutramine is a serotonin and noradrenaline reuptake inhibitor (SNRI). It is an antiobesity drug, which decreases calorie intake and increases energy expanditure. Sibutramine antagonizes MPTP-induced dopamine depletion in mouse brain.
특징 및 장점
This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
Jamie D Dunn et al.
Journal of pharmaceutical and biomedical analysis, 54(3), 469-474 (2010-10-14)
In response to recent incidents of undeclared sibutramine, an appetite suppressant found in dietary supplements, we developed a method to detect sibutramine using hand-held ion mobility spectrometers with an analysis time of 15 s. Ion mobility spectrometry is a high-throughput
Cibele S Borges et al.
PloS one, 8(6), e66091-e66091 (2013-06-19)
Sperm acquire motility and fertility capacity during epididymal transit, under the control of androgens and sympathetic innervations. It is already known that the acceleration of epididymal sperm transit time can lead to lower sperm quality. In a previous work we
Hiroaki Yashiro et al.
PloS one, 11(11), e0166198-e0166198 (2016-11-11)
Obesity is now recognized as a state of chronic low-grade inflammation and is called as metabolic inflammation. Delta-5 desaturase (D5D) is an enzyme that metabolizes dihomo-γ-linolenic acid (DGLA) to arachidonic acid (AA). Thus, D5D inhibition increases DGLA (precursor to anti-inflammatory
Alexandre V Ivachtchenko et al.
Journal of Alzheimer's disease : JAD, 58(4), 1043-1063 (2017-05-28)
Discovery of 5-HT6 receptor subtype and its exclusive localization within the central nervous system led to extensive investigations of its role in Alzheimer's disease, schizophrenia, and obesity. In the present study, we present preclinical evaluation of a novel highly-potent and
Cristiani F Bortolatto et al.
Psychopharmacology, 232(13), 2239-2249 (2015-01-08)
The searching for safe and effective antiobesity drugs has been the subject of intense research. Previous studies have shown several pharmacological applications of organoselenium compounds; however, their possible anorectic-like actions have not been investigated. This study aims to investigate the
Chromatograms
application for HPLCapplication for HPLC자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.