S9666

Sphingosine 1-phosphate

≥95% (TLC), powder, lipid second messenger

• 동의어(들): (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol 1-phosphate, D-erythro-Sphingosine 1-phosphate
• 실험식(Hill 표기법): C₁₈H₃₈NO₅P
• CAS Number: 26993-30-6
• Molecular Weight: 379.47
• MDL number: MFCD00270077
• UNSPSC 코드: 12352211
• PubChem Substance ID: 24899853
• NACRES: NA.77

속성

• product name: Sphingosine 1-phosphate, ≥95%, powder
• Quality Level: 300
• 분석: ≥95%
• 형태: powder
• 저장 온도: −20°C
• SMILES string: CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)COP(O)(O)=O
• InChI: 1S/C18H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h14-15,17-18,20H,2-13,16,19H2,1H3,(H2,21,22,23)/b15-14+/t17-,18+/m0/s1
• InChI key: DUYSYHSSBDVJSM-KRWOKUGFSA-N
• 유전자 정보: human ... S1PR1(1901) , S1PR2(9294) , S1PR3(1903) , S1PR4(8698) , S1PR5(53637)

설명

생화학적/생리학적 작용

A lipid second messenger that binds to S1P₁ and S1P₃ receptors. Mobilizes intracellular Ca²⁺ stores and decreases cellular cAMP. Activates phospholipase D. S1P stimulates the migration of endothelial cells but inhibits the migration of other cell types. Induces angiogenesis.

특징 및 장점

This compound is featured on the Lysophospholipid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves