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Merck
모든 사진(2)

Key Documents

S7951

Sigma-Aldrich

Ovalbumin (257-264) chicken

≥97% (HPLC), lyophilized powder, antigenic peptide 

동의어(들):

L-seryl-L-isoleucyl-L-isoleucyl-L-asparaginyl-L-phenylalanyl-L-a-glutamyl-L-lysyl- L-Leucine trifluoroacetate, OVA (257 - 264), SIINFEKL trifluoroacetate salt, Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu trifluoroaceate, pOV8

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About This Item

실험식(Hill 표기법):
C45H74N10O13 · xC2HF3O2
CAS Number:
Molecular Weight:
963.13 (free base basis)
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77

product name

Ovalbumin (257-264) chicken, ≥97% (HPLC)

Quality Level

분석

≥97% (HPLC)

형태

lyophilized powder

색상

white to off-white

solubility

H2O: >1 mg/mL

저장 온도

−20°C

SMILES string

OC(=O)C(F)(F)F.CC[C@H](C)[C@H](NC(=O)[C@@H](N)CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(O)=O

InChI

1S/C45H74N10O13.C2HF3O2/c1-7-25(5)36(55-44(66)37(26(6)8-2)54-38(60)28(47)23-56)43(65)52-32(22-34(48)57)42(64)51-31(21-27-14-10-9-11-15-27)41(63)50-30(17-18-35(58)59)40(62)49-29(16-12-13-19-46)39(61)53-33(45(67)68)20-24(3)4;3-2(4,5)1(6)7/h9-11,14-15,24-26,28-33,36-37,56H,7-8,12-13,16-23,46-47H2,1-6H3,(H2,48,57)(H,49,62)(H,50,63)(H,51,64)(H,52,65)(H,53,61)(H,54,60)(H,55,66)(H,58,59)(H,67,68);(H,6,7)/t25-,26-,28-,29-,30-,31-,32-,33-,36-,37-;/m0./s1

InChI key

BRUCWCULSHVYBQ-VPZPQSBKSA-N

Amino Acid Sequence

Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu

애플리케이션

Ovalbumin (257-264) chicken has been used to trigger T cell activation in immunology studies.
Ovalbumin (257-264) chicken has been used:
  • to sensitize mice to generate an asthmatic model
  • in the stimulation of splenocytes
  • for treating dendritic cells to be used as a positive control in cross-presentation studies

생화학적/생리학적 작용

Ovalbumin (257-264) chicken is an antigenic peptide and triggers immune response. Administration of the ovalbumin peptide in pregnant mice helps in surpassing ear development anomalies.
SIINFEKL is a class I (Kb)-restricted peptide epitope of ovalbumin (OVA); the ovalbumin fragment is presented by the class I MHC molecule, H-2Kb.

기타 정보

Lyophilized from 0.1% TFA in H2O

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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Primary in vivo responses to ovalbumin. Probing the predictive value of the Kb binding motif.
Lipford GB, et al.
Journal of Immunology, 150(4), 1212-1222 (1993)
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관련 콘텐츠

We offer agonists, antagonists, modulators and other bioactive small molecules for immune system signaling target identification and validation, as well as a variety of antibiotics, antivirals, and antifungals.

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