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Merck
모든 사진(1)

주요 문서

S7632

Sigma-Aldrich

N-Succinyl-Ala-Ala-Val-Ala p-nitroanilide

protease substrate

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About This Item

실험식(Hill 표기법):
C24H34N6O9
CAS Number:
Molecular Weight:
550.56
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:
NACRES:
NA.32

분석

≥98% (TLC)

양식

powder

solubility

DMF: 10 mg/mL, clear, colorless

UniProt 수납 번호

저장 온도

−20°C

SMILES string

CC(C)C(NC(=O)C(C)NC(=O)C(C)NC(=O)CCC(O)=O)C(=O)NC(C)C(=O)Nc1ccc(cc1)N(=O)=O

InChI

1S/C24H34N6O9/c1-12(2)20(24(37)27-14(4)22(35)28-16-6-8-17(9-7-16)30(38)39)29-23(36)15(5)26-21(34)13(3)25-18(31)10-11-19(32)33/h6-9,12-15,20H,10-11H2,1-5H3,(H,25,31)(H,26,34)(H,27,37)(H,28,35)(H,29,36)(H,32,33)

InChI key

IYHHIHIBYVIDMJ-UHFFFAOYSA-N

유전자 정보

mouse ... Npy(109648)

일반 설명

N-Succinyl-Ala-Ala-Val-Ala p-nitroanilide is a chromogenic and a synthetic peptide substrate for proteases, elastase and subtilisin.

애플리케이션

N-Succinyl-Ala-Ala-Val-Ala p-nitroanilide has been used as a synthetic peptide substrate for:
  • Bacillus pumilus alkaline protease (DHAP)
  • mesophilic subtilisin Carlsberg (sC) to assess the hydrolytic activity of wild-type and mutant sC
  • Pseudoalteromonas arctica cold-active protease (Pro21717)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Min-Yuan Wan et al.
Applied biochemistry and biotechnology, 159(2), 394-403 (2009-01-10)
An alkaline protease (DHAP) from Bacillus pumilus has shown great potential in hide dehairing. To get better insights on its catalytic properties for application, the substrate specificity and thermostability were investigated using five natural proteins and nine synthetic peptides. The
William R Swindell et al.
The Journal of investigative dermatology, 140(3), 602-614 (2019-08-30)
Zingerone (Z) is a phenolic alkanone derived from natural sources with anti-inflammatory and antioxidant effects. Acetyl zingerone (AZ) is a recently designed molecule that shares structural features with Z but is expected to have improved stability and antioxidant function. This
Semra Kocabiyik et al.
Bioscience, biotechnology, and biochemistry, 70(1), 126-134 (2006-01-24)
An intracellular serine protease produced by Thermoplasma (Tp.) volcanium was purified using a combination of ammonium sulfate fractionation, ion exchange, and alpha-casein agarose affinity chromatography. This enzyme exhibited the highest activity and stability at pH 7.0, and at 50 degrees

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