R5258

Riboflavin Binding Protein from chicken egg white

lyophilized powder

• 동의어(들): Binding Protein, Chicken Egg White Protein, Riboflavin Protein
• UNSPSC 코드: 12352202
• NACRES: NA.26

속성

• 생물학적 소스: chicken egg white
• Quality Level: 200
• 양식: lyophilized powder
• 농도: ≥50% protein (biuret)
• UniProt 수납 번호: P02752
• 저장 온도: −20°C
• 유전자 정보: chicken ... RBP(396449)

설명

일반 설명

Riboflavin Binding Protein (RBP) comprises of 19 cysteines and corresponds to a molecular weight of 30 kDa. Egg white RBP is produced in the oviduct cells. Chicken egg white RBP contains an N-terminal ligand binding domain and a C-terminal phosphorylated motif.

Riboflavin binding protein (RBP) transports riboflavin through the bloodstream of the laying hen into the eggs, where the vitamin is essential for embryonic growth and development. RBP consists of a single polypeptide chain containing 9 disulfide bonds. It is a glycoprotein containing ~14% carbohydrate, with sugar moieties including galactose, mannose and glucosamine, and is phosphorylated.

애플리케이션

Riboflavin Binding Protein from chicken egg white may be used in fluorescence quenching experiments.

생화학적/생리학적 작용

Riboflavin Binding Protein (RBP) is crucial for normal embryo development. RBP interacts with riboflavin and its analogs. The RBP-riboflavin complex is stabilized by interaction between the isoalloxazyne ring of riboflavin and the tyrosine 75 and tryptophan 156 of residues of RBP. RBP elicits sweet supressing functionality and may interact with the sweet taste receptor.

Riboflavin binding protein binds to flavokinase and regulates its activity.

제조 메모

Supplied as the riboflavin-depleted apo-form.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)