재조합
expressed in E. coli
Quality Level
양식
buffered aqueous glycerol solution
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
유전자 정보
human ... RALB(5899)
애플리케이션
Can be used as a control in immunoblotting and in protein binding assays.
생화학적/생리학적 작용
Ral B (21 kDa, native), a member of the Ras-like GTP binding protein family, is a crucial link in intracellular signaling cascades.
Ral B has been implicated in invasion and metastasis of human cancer cells. Reports have shown that depletion of Ral B by siRNA results in significantly reduced migration rates of tumor cells, while constitutively active Ral B promoted migration.
기타 정보
GST-tagged Ras-like fusion protein
물리적 형태
Supplied as a solution in 50 mM Tris, pH 7.5, containing 150 mM sodium chloride, 10 mM magnesium chloride, 1 mM DTT, and 10% glycerol.
Storage Class Code
10 - Combustible liquids
가장 최신 버전 중 하나를 선택하세요:
Gary Oxford et al.
Cancer research, 65(16), 7111-7120 (2005-08-17)
The Ral family of small G proteins has been implicated in tumorigenesis, invasion, and metastasis. However, little emphasis has been placed on clarifying the individual roles of the two Ral proteins, RalA and RalB, in these processes in view of
Y Takai et al.
Physiological reviews, 81(1), 153-208 (2001-01-12)
Small GTP-binding proteins (G proteins) exist in eukaryotes from yeast to human and constitute a superfamily consisting of more than 100 members. This superfamily is structurally classified into at least five families: the Ras, Rho, Rab, Sar1/Arf, and Ran families.
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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